jun

(abbr. from Japanese ju-nana for 17) The oncogene v-jun is the putative transforming gene of avian sarcoma virus 17 which induces fibrosarcomas in chickens and can transform a number of avian cell types in vitro by the action of v-jun.

The human c-jun gene maps to chromosome 1p31-p32. The human gene does not contain introns and displays approximately 80 % sequence identity with the viral gene. jun belongs to a family of related genes that includes junD and junB.

jun encodes the transcription factor AP-1 [activator protein-1] which recognizes the AP-1 ... ... ... ...
 
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Entry last modified: July 1999