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immunomodulation

[immunomodulatory, immunomodulating]

A general term used to describe the specific and unspecific alterations of immune system functions by a very heterogeneous group of microbial or synthetic substances and products of activated cells such as cytokines or Thymic hormones.

Immunomodulators are called also biological response modifiers (abbr. BRM). Their mechanism of action usually involves a complicated interplay of various regulator and effector systems. Immunomodulators may enhance (immunoprophylaxis, immunostimulation), restore (immunosubstitution, immunorestauration) or suppress (immunosuppression, immunodeviation) immunological reactivity.

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