hRFI

[human Ring Finger homologous to Inhibitor of apoptosis protein] also simply: RFI [RING finger homologous to inhibitor of apoptosis protein]. This protein has been identified in a two-hybrid yeast screening, using a human homolog of the Drosophila melanogaster tumor suppressor lethal(2) tumorous imaginal discs, human TID1L, as bait (Sasaki et al, 2002). The protein contains a C-terminal RING domain similar to IAP family members. hRFI lacks a BIR domain found in other members of the IAP family and known to be required for the anti-apoptotic ... ... ... ...
 
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Entry last modified: March 2013