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formaecins

Formaecin-1 (GRPNPVNNKPTPHPRL) and Formaecin-2 (GRPNPVNTKPTPYPRL) are antibacterial peptides identified in the Red bulldog ant Myrmecia gulosa. These two peptides are synthesized in response to bacterial infections. Both peptides are rich in proline (approximately 30 %), and carry N-acetylgalactosamine O-linked to a conserved threonine residue. Non-glycosylated isoforms are markedly less bioactive. Both peptides are active only against growing Escherichia coli. They are inactive against stationary cells, Gram-positive bacteria, the yeast Candida albicans, two species of mammalian ... ... ... ... ... Subscribe to continue reading! ... ...

 

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