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[elevated during infection] This Drosophila melanogaster protein, encoded by gene CG32185, has been shown to play a role in innate immunity (Gordon et al, 2008) behaving in some aspects as other antimicrobial peptides but also like a cytokine involved in pathogen-mediated pathogenesis. The expression of expression is upregulated in flies with a wntD mutation, which cause susceptibility to Listeria monocytogenes infection. Edin is also expressed more highly during infection of wild-type flies with wild-type Salmonella typhimurium than with a less pathogenic mutant strain, and its expression is regulated in part by the imd ... ... ... ...
 
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Entry last modified: March 2016