cGAS
[cyclic GMP-AMP synthase]; also: cGAMP synthase, 2'3' cyclic GMP-AMP synthase, cyclic guanosine monophosphate/adenosine monophosphate synthase. The approved gene symbol is MB21D1 [MAB21 domain-containing protein 1]. In databanks the gene is found also as C6ORF150 [chromosome 6 open reading frame 150]. cGAS is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP; 2’-3’-cyclic GMP-AMP, or G(2’-5’)pA(3’-5’)p) from ATP and GTP (enzyme designation EC2.7.7.86) (Sun et al, 2013; Kranzusch et al, 2013, 2014; Civril et al, 2013).
The gene has been cloned
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