XS cell growth factor |
Xsl |
nidoviral uridylate-specific endoribonuclease |
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[X-linked severe combined immunodeficiency] abbr. also SCIDX. This disorder is known also as Swiss-type agammaglobulinemia or thymic epithelial hypoplasia (Nezelof, 1992).
XSCID is a severe combined immunodeficiency syndrome characterized by the inactivation of the X chromosome (Conley et al, 1988, 1990; Goodship et al, 1988; Puck et al, 1987) and mutations in the gamma chain of the IL2 receptor, IL2RG [IL2 receptor-gamma] (Leonard, 1996). This subunit is also shared by receptors for other interleukins (see: common gamma). See also: Immunodeficient mice. In the nomenclature of CD antigens
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