VGlut3 amacrine cells |
VGMAPG |
SP-D |
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This peptide with the sequence VSCNGVCSPFEMPPCGSSACRCIPYGLVVGNCRHPSG has been isolated from germinating pea seed extracts of peas (Pisum sativum).
Jiang H et al (2015) have reported that Vglycin promotes the proliferation of pancreatic Beta-cells and suppresses apoptosis and dedifferentiation of these cells. It promotes the restoration of Beta-cells in both young streptozotocin-induced type 1 diabetic SD rats and in aged high-fat diet with (or without) stretozotocin-induced type 2 diabetic C57BL/6 mice. This is accompanied by activating the insulin receptor and corresponding transcription factors. Impaired insulin sensitivity and glucose tolerance in aged T2DM mice
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