VEGF-C

[vascular endothelial growth factor C] VEGF-2 is the same as VEGF-C. The protein is being referred to also as flt-4 ligand (abbr. flt-4L).

Chilov et al (1997) have cloned the human and mouse genes for VEGF-C. Both genes consist of seven exons. The VEGF homology domain of VEGF-C is encoded by exons 3 and 4. Exons 5 and 7 encode cysteine-rich motifs of the type C6C10CRC, and exon 6 encodes additional C10CXCXC motifs typical of a silk protein. A putative alternatively spliced rare RNA form lacking exon 4 has been identified in ... ... ... ...
 
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Entry last modified: December 2010