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VEGF-162

[VEGF-A162] [Vascular endothelial growth factor-162] VEGF-162 (162 amino acids) is a splice variant of VEGF detected in human A431 ovarian carcinoma cells. VEGF-162 is induces proliferation of endothelial cells in vitro and angiogenesis in vivo, as determined by the alginate beads assay (Lange et al, 2003).

VEGF-162 binds less efficiently than VEGF-145, but more efficiently than VEGF-165, to a natural basement membrane produced by corneal endothelial cells.

See also: Angiogenesis Dictionary section of this encyclopedia for other entries directly bearing on factors and processes involved in the generation of new blood vessels ... ... ... ... ... Subscribe to continue reading! ... ...

 

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