TGFBR5
[TGF-beta receptor 5; transforming growth factor-beta receptor 5; TGF-beta receptor type 5; type 5 TGF-beta receptor] TGFBR5 is coexpressed with other TGF-beta receptors (TGFBR1, TGFBR2, TGFBR3) in most cell types (O'Grady et al, 1991) and serves as the receptor for IGFBP3, mediating growth inhibition upon IGFBP3 stimulation that is independent of IGF and sensitive to TGF-beta antagonists (Leal et al, 1997; Leal et al, 1999; Wu et al, 2000). TGFBR5 is identical with LRP1 (Huang et al, 2003; Leal et al, 1997). In databanks the receptor is being referred to also as
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