TGF-beta-LAP

[TGF-beta latency-associated peptide]

The different isoforms of TGF-beta are synthesized initially as large precursors (pro-TGF-beta) consisting of a signal peptide, an N-terminal latency-associated peptide (abbr. LAP), and the C-terminal mature peptide (Kingsley, 1994).

The TGF-beta-LAP sequences are being referred to as

TGF-beta-1-LAP [TGF-beta-1 latency-associated peptide] (often also just beta-1-LAP [beta-1 latency associated peptide])

TGF-beta-2-LAP [TGF-beta-2 latency-associated peptide] (often also just beta-2-LAP)

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Entry last modified: May 2015