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Syphaxin

abbr. spx. This antimicrobial peptide, GVLDILKGAAKDLAGHVATKVINKIamide, has been isolated from the skin of the South American frog Leptodactylus syphax (Dourado FS et al, 2007). In databanks it is known also as Ocellatin-S1 (see: ocellatins). Shorter fragments spx(1-22) (Syphaxin(1-22)) and spx(1-16) (Syphaxin(1-16)) show weak activity against Escherichia coli and Staphylococcus aureus, showing low minimal inhibitory concentration and no significant toxicity towards blood cells, including both leukocytes and erythrocytes,.

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