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SgI-29

This peptide (HNKQEGRDHDKSKGHFHRVVIHHKGGKAH) is derived by proteolytic cleavage of Semenogelin-1, one of the most abundant proteins in human seminal plasma that plays a key role in sperm coagulation and spermatozoon immobilization. SgI-29 corresponds to Semenogelin-1 (85-113). The peptide possesses strong antibacterial activity towards various bacterial strains (Zhao et al, 2008).

For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.

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