SP5029

This peptide, LLIVALLFILSWL (Leu-Leu-Ile-Val-Ala-Leu-Leu-Phe-Ile-Leu-Ser-Trp-Leu), is one of several endogenous peptides derived from proteins containing a conserved somatotropin domain and selected for inhibition of angiogenesis and lymphangiogenesis using in vitro proliferation, migration, adhesion and tube formation assays with blood and lymphatic endothelial cells (Lee et al, 2011). The peptide is derived from NPFFR2 [neuropeptide FF receptor 2] and corresponds to NPFFR2(276-288) [neuropeptide FF receptor 2(276-288)]. The peptide potently inhibits the proliferation of ... ... ... ...
 
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Entry last modified: June 2015