SP-40,40 |
SP5028 |
wide arbor neurons |
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This peptide, RLRLLTLQSWLL, is one of several endogenous peptides derived from proteins containing a conserved somatotropin domain and selected for inhibition of angiogenesis and lymphangiogenesis using in vitro proliferation, migration, adhesion and tube formation assays with blood and lymphatic endothelial cells (Lee et al, 2011). The peptide is derived from IL17RC [interleukin-17 receptor C; IL17 receptor C] and corresponds to IL17RC(376-387). The peptide shows antiproliferative activities in a lymphatic endothelial cell proliferation assay and thus can inhibit
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