Sestrin-2 |
Setagin |
CBP-15 |
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[SH3 domain-containing gene expressed in tumorigenic astrocytes] SETA is an adapter protein that contains a SH3 domain. The approved gene symbol is SH3KBP1 [SH3 domain kinase binding protein 1]. Take et al (2000) have cloned the gene encoding SETA as CIN85 [Cbl-interacting protein 85 kDa], which encodes a protein that interacts with the c-cbl oncogene that is known to play a role in mediating the EGF receptor signaling cascade.
SETA has been described independently as Ruk [regulator of ubiquitous kinase
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