Pantinin-3 |
Panton-Valentine leukocidin |
tumor-specific protein 180 |
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Pantinin-1 [GILGKLWEGFKSIV], Pantinin-2 [IFGAIWKGISSLL], and Pantinin-3 [FLSTIWNGIKSLL] are alpha-helical, cationic and amphipathic molecules identified from the Emperor scorpion Pandinus imperator. All the three peptides possess relatively strong activities against Gram-positive bacteria and a fungus, but are only very weakly antimicrobial for Gram-negative bacteria. The hemolytic activity of all three peptides is very low or mild. Pantinin-3 potently inhibits the growth of vancomycin-resistant Enterococcus S13
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also:
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