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PRDM1

[PR domain containing 1; PR domain-containing protein 1] also: PR domain zinc finger protein 1. PRDM1 has been identified as a transcriptional repressor that binds specifically to the PRDI element in the promoter of the IFN-beta gene (Keller and Maniatis, 1991). The protein is known also as PRDI-BF1 [Positive regulatory domain I-binding factor 1; PRDI-binding factor 1, PR domain-containing protein 1, PR domain zinc finger protein 1] and is the human homolog of murine BLIMP1 [B-lymphocyte-induced maturation protein-1] (see below) (Huang S, 1994). The ... ... ... ... ... Subscribe to continue reading! ... ...

 

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