PLUNC

[palate lung and nasal epithelium clone] PLUNC is a secreted protein (Campos et al, 2004) with structural homology to known mediators of host defense against Gram-negative bacteria such as LBP (LPS binding protein; lipopolysaccharide-binding protein) and Bactericidal/permeability-increasing protein (Bingle and Gorr, 2004). Bingle and Craven (2002) have reported the existence of a family of related PLUNC genes encoded by adjacent genes found within a 300 kb region of human chromosome 20. Bingle and Craven (2003) have described a family of at least 14 PLUNC genes localized on chromosome 20 (in humans), 2 (in mice) or 3 (in rats ... ... ... ...
 
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Entry last modified: December 2010