PLDSVYGTHGMSGFA |
Pleckstrin homology domain |
anti-microRNAs |
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[paraneoplastic limbic encephalitis antigen 21] This antigen on neural cells has been identified by Sakai et al (1994) by means of autoantibodies found in the serum of a patient with paraneoplastic limbic encephalitis. The antigen is identical with HuC [Hu antigen C] (approved gene symbol: ELAVL3 [embryonic lethal abnormal vision homolog 3], which is a homolog of a Drosophila gene required for neuronal development and maintenance (see: ELAV) (King et al, 1994). Mouse and human proteins are 96 % identical (Abe et al, 1996). The protein is one of several RNA-binding proteins that attach to short-lived mRNAs for cytokines and
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