PAP-2

[pancreatitis-associated protein-2] This rat protein is related to PAP-1 (Frigerio et al, 1993). PAP-2 is a member of a multigene family of proteins expressed in several tissues, which includes PAP-1, PAP-3, and Lithostathine. Bodeker et al (1999) have reported that PAP-1, PAP-2, and PAP-3 can form heterodimers. Another designation for this protein is REG3A [REG3-alpha] (see: REG3 [regenerating islet-derived-3]).

Alternative splicing of PAP-2 yields two different proteins (Vasseur et al, 1995). The gene is overexpressed by the pancreas during acute pancreatitis but not in intestinal tissues (unlike the related PAP-1 ... ... ... ...
 
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Entry last modified: March 2005