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Nesidioblasts

[Nesidioblast]

This term refers to cells in pancreatic islands of Langerhans associated with nesidioblastosis (referred to also as persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI), congenital hyperinsulinism, nesidiodysplasia, and islet cell dysmaturation syndrome). The syndrome is associated with abnormal hyperplastic beta-cells with giant nuclei. A deficiencty of somatostatin cells (D cells) has been noted also (for overview see: Zumkeller, 1999; Milner, 1996).

For related information of interest see also: Cell types Dictionary, Cell lines in Cytokine Research, Cell culture.

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