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NKLP27

This antimicrobial peptide from tongue sole (Cynoglossus semilaevis) NK-lysin gene (named CsNKL1) (Zhang et al, 2013) shares little sequence identity with known NK-lysin peptides from fish, chicken, bovine, and porcine NK-lysin. The peptide, KVKARLIKICNKIGFLKSRCHKFVITH, has been shown to modulate immune response by upregulating the expression of immune genes including those known to be involved in antibacterial and antiviral defense. Factors with upregulated expression in response to NKLP27 include TLR-9, MyD88 (a universal adapter protein in the signaling pathways of almost all Toll-like receptors), ... ... ... ... ... Subscribe to continue reading! ... ...

 

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