metallothionein-4 |
metallothionein-1/2 |
DRAGON-like muscle |
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Metallothioneins constitute a family of low molecular weight (67 kDa) metal-binding proteins, characterized by their unusually high cysteine content (approximately 30%) (Coyle et al, 2002). There are four isoforms, metallothionein-1 (MT-1), metallothionein-2 (MT-2), metallothionein-3 (MT-3), metallothionein-4 (MT-4), which show different expression profiles. MT-3 and MT-4 are expressed constitutively despite signal changes in vitro or in vivo (Haq et al, 2003).
Metallothionein-1 and metallothionein-2 are expressed in most tissues (Coyle et al, 2002). Metallothionein-3
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