Mecasermin
This is recombinant human IGF-1 (Anonymus, 1999), which is approved in the US for the long-term treatment of growth failure in children with severe primary IGF-1 deficiency or with growth hormone gene deletion who have developed neutralizing antibodies to growth hormone, and in the Eropean Union for the long-term treatment of growth failure in children and adolescents with severe primary IGF-1 deficiency (Keating GM, 2008).
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