MTF

[metanephros-derived tubulogenic factor] The mRNA (759 nucleotides) encoding this factor has been identified in developing mouse kidney. Addition of recombinant MTF protein promotes ureteric bud branching in cultured metanephroi and increases cell proliferation. Inhibition of MTF with antisense oligonucleotides impair ureteric bud branching by cultured metanephroi.

Sequence analysis shows that the encoded protein is a component of the large subunit of the 55S mitoribosome complex and corresponds to MRPL47 [mitochondrial ribosomal protein L47; also 39S ribosomal protein L47]. The authors refer to the protein also as MTF/L47. The protein. The human homolog ... ... ... ...
 
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Entry last modified: February 2019