MP-locomotion inhibiting entamoeba product |
MPMANLLLLI |
GP1BB |
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[myeloproliferative leukemia virus] MPLV is a murine replication-defective acute leukemogenic retrovirus. It harbors a viral oncogene called v-mpl or MPL [Myeloproliferative leukemia protein]. The corresponding cellular counterpart (c-MPL) is expressed predominantly in hematopoietic tissues, in particular in immature hematopoietic precursor cells (see also: hematopoiesis), but also in spleen, and fetal liver. MPL is not expressed in the thymus. The human oncogene maps to chromosome 1p34. Its sequence is strongly conserved among mammalians (81 % amino acid identity between humans and
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