Mcub |
MD10 |
classically activated macrophages |
||
[myeloid differentiation factor 2] This protein has been identified by Shimazu et al (1999). The approved gene symbol for this protein is Ly96 [lymphocyte antigen 96 homolog].
Expression of MD-2 enhances TLR4 dependent activation of NF-kappa-B. MD-2 binds with high affinity to the extracellular domain of the TLR4 receptor and is required for maximal responsiveness of the receptor to bacterial lipopolysaccharides. MD-2 has been shown to complex with TLR2 / CD14 and TLR4 /CD14 and appears to discriminate between pathogen-associated molecular patterns (PAMPs) and
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R