leptocytes |
leptomeningeal cells |
SMAP-6 |
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Leptoglycin is a neutral Glycine/Leucine-rich antimicrobial peptide (GLLGGLLGPLLGGGGGGGGGLL) from skin secretion of the South American frog Leptodactylus pentadactylus (Sousa et al, 2009). Leptoglycin inhibits the growth of Gram-negative bacteria Pseudomonas aeruginosa, Escherichia coli and Citrobacter freundii, but does not show antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Micrococcus luteus and Enterococcus faecalis), yeasts (Candida albicans, Candida tropicalis), and dermatophytes fungi (Microsporum canis, Trichophyton rubrum). The peptide is not hemolytic for red blood cells.
For other proteins/peptides with functions in innate immunity
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