LGF-2 |
LGI1-like protein 2 |
LF21-31 |
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[leucine-rich glioma inactivated 1] This gene has been identified by Chernova et al (1998) from a rearranged chromosomal region in a glioblastoma cell line. This rearrangement, which is observed also in other gliobastoma cell lines, leads to the complete absence of protein expression. LGI1 is the product of a causative gene for ADLTE [autosomal dominant lateral temporal lobe epilepsy] (known also as ADPEAF [autosomal dominant partial epilepsy with auditory features]
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