KM102

This human stromal cell line (see also: hematopoiesis) has been obtained from adherent bone marrow cell layers of Dexter-type long-term BMC (bone marrow culture) after immortalisation with SV40.

The cells have been shown to express GM-CSF (see also: KM102-BPA) and IL11 mRNA. KM102 cells are a source of IL11 (see: AGIF (adipogenesis inhibitory factor). The cells also produce small amounts of G-CSF, and production of G-CSF is induced by IL1 and, to a lesser extent by bacterial endotoxins.

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Entry last modified: January 2002