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KLPGWSG

This short peptide has been identified by applying the Phage Display technique to murine neural stem cells. KLPGWSG binds molecules expressed on the cell surface of murine adult neural stem cells. This peptide in solution enhances per se cell differentiation towards the neuronal phenotype. Self-assembling peptides functionalized with KLPGWSG have been used to obtain nanostructured hydrogels supporting murine neural stem cells differentiation in vitro. When the scaffold stiffness is comparable to that of the brain in vivo, one of the scaffolds enhances neuronal differentiation of neural stem cells ... ... ... ... ... Subscribe to continue reading! ... ...

 

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