IL17E |
IL17 family |
TAN |
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[interleukin-17F] IL17F is a member of the IL17 family of cytokines produced by activated T-cells and monocytes (Starnes et al, 2001). The gene has been cloned independently as ML-1. For a heterodimer consisting of IL17A and IL17F see: IL17A/F.
Kuestner et al (2007) have reported that IL17F uses the IL17RC receptor, which also binds IL17A. A soluble form of IL17RC effectively blocks binding of both IL17A and IL17F and inhibits signaling in response to these cytokines.
IL17F markedly inhibits angiogenesis of human
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