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IL17D

[interleukin-17D] Note: databanks contain an entry (Accession number AY078238; Hadj-Slimane and Bobe) with the designation IL27. The reported sequence is IL17D.

IL17D is a secreted cytokine with homology to the IL17 family of proteins. IL17D is expressed preferentially in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas. IL17D induces the production of IL6, IL8, and GM-CSF by endothelial cells (Starnes et al, 2002). The recombinant factor inhibits the development of myeloid progenitor cells in a colony formation assay (see also: Hemtaopoiesis).


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