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IE63 |
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[immediate early protein 2] This protein is encoded by open reading frame UL122 of human cytomegalovirus (Cytomegalovirus IE2 protein; Cytomegalovirus UL122 protein). This 86 kDa protein is being referred to in many publications also as IE2-86 or IE86 [Cytomegalovirus immediate early 86 protein]. It is involved in transcriptional regulation, controlling CMV early transcription. The activity of IE2 is greatly affected by phosphorylation (Barrasa et al (2005). IE2 is an immediate-early gene product that is absolutely indispensable for productive viral replication (Heider et al, 2002; Marchini et al, 2001).
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