HC21 |
HCA2 |
TRIM domain |
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[Hematopoietic cell antigen] HCA is expressed on 40 - 70 % of CD34(+) fetal and adult bone marrow cells and mobilized peripheral blood cells. HCA is expressed by the most primitive subsets of CD34(+) cells, including all cell types that show little staining with rhodamine-123, Thy1(+) cells, and CD38(-) and CD38(low) CD34(+) adult bone marrow cells. HCA is detected also on myeloid progenitors but not on early B-cell progenitors.
Human HCA is recognized by the F84.1 monoclonal antibody and has been shown to be the
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