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Gomesin

Gomesin is a small cationic antimicrobial peptide (QCRRLCYKQRCVTYCRGR) with two disulfide bridges isolated from the hemocytes of the unchallenged tarantula spider Acanthoscurria gomesiana (Silva et al, 2000). The gomesin gene is expressed constitutively in hemocytes. The gene product is processed from a larger precursor and is localized in hemocyte granules (Lorenzini et al, 2003).

Gomesin shows marked sequence similarities to antimicrobial peptides from other arthropods such as tachyplesin and polyphemusin from horseshoe crabs and androctonin from scorpions. It also shows sequence similarities to porcine protegrins ... ... ... ... ... Subscribe to continue reading! ... ...

 

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