COPE Media Kit

Cope Home
Previous entry:
Next entry:
Random entry:
hypocretin 1
Search COPE:


this protein is a major (one of eight) excreted/secreted dense granule antigen of the obligate intracellular protozoan parasite Toxoplasma gondii. GRA1 is a 23 kDa calcium-binding protein, identified originally as antigen P24. It is secreted by tachyzoites and bradyzoites (Cesbron-Delauw et al, 1989). It induces humoral immune responses in mice and humans in the chronic phase of the infection (Cesbron-Delauw et al, 1989). GRA1 is protective in animal models of infection (Duquesne et al, 1991; Supply et al, 1999). Immunization of sheep with recombinant Mycobacterium bovis BCG producing and secreting GRA1 results in specific, partially protective cellular immune responses characterized by the production of IFN-gamma (Supply et al, 1999).

Lin et al (2010) have demonstrated that the expression of GRA1 in the endoplasmic reticulum of ... ... ... ... ... Subscribe to continue reading! ... ...


Content view restricted !

COPE - with 54500+ entries the most comprehensive cell-to-cell communication knowledge base

Extensive In-depth and In Context Information covering terminology, nomenclature, concepts, strategies & complexities of cellular communication, including Acute phase proteins | Angiogenesis | Antimicrobial & host defense peptides | Apoptosis & other forms of cell death | CD antigens | Cell lines | Cell reprogramming | Chemokines | Cryptides | Cytokines & Growth factors | CytokineTopics | Eukaryotic cell types & expression profiles | Hematopoiesis | Hormones | Inflamation & inflammatory mediators | Innate Immunity | Metalloproteinases | Microvesicles / Microparticles | Moonlighting proteins & cryptides | Neuropeptides | Non-coding RNAs | Pathogenicity & Virulence Factors | Pattern recognition receptors | Peptide sequences | Protein domains | Regulatory peptide factors | Viroceptors | Virokines and more.

Full COPEing for subscribers:

Access to Alphabet bar, Freetext search, Leafing/browsing functions, Internal Backlinking, Topic-specific introductions, Topic-specific integrated subdictionaries, Scientific references with PubMed links

with a 15 USD/month subscription at

See example pages at the bottom of the home page
The others just sisyphos around


Copyright © 1997-2021. All rights reserved by Dr H Ibelgaufts, the author of COPE - Cytokines & Cells Online Pathfinder Encyclopaedia


SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials
# A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

              Created, developed, and maintained by Dr H Ibelgaufts              
About the author of COPE
  |    Contact COPE   |    Terms & Conditions

U L T R A   P O S S E    N E M O   O B L I G A T U R

cope.cgi Version 1.41 [08.12.2020]. (c) JI. Powered by Perl 5.028001. key=22129