gloverin-like protein 4 |
GLP-1 neurons |
ADAM metallopeptidase domain 3 |
||
[glucagon-like peptide-1] GLP-1, formerly called insulinotropin (Mojsov et al, 1987), is a peptide hormone (HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG; His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly) encoded by the preproglucagon gene. The protein corresponds to PG(78-107) [proglucagon(78-107)] (see also: Holst, 1997). Both pancreas and intestine contain GLP-1 in at least two forms of 31 amino acids (GLP-1(7-37) [glucagon-like peptide-1(7-37)], 7-37, or
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