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FGG(401-413)

[fibrinogen(401-413); fibrinogen-gamma(401-413)] This peptide, KKTSMKIIPFTRL, derived from fibrinogen (fibrinogen-gamma subunit), has been identified by Bishop et al (2015) in the plasma of the American alligator, Alligator mississippiensis. It shows strong antimicrobial activity against Escherichia coli. This peptide shows a decrease in potency relative to FGG(398-413) against Pseudomonas aeruginosa, Bacillus cereus, and Staphylococcus aureus.

For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.

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