Engrailed

This Drosophila melanogaster protein, a transcription factor containing homeodomains, is encoded by the CG9015 gene, a member of a larger family of homeotic genes. Garcia-Bellido and Santamaria (1972) have reported that inactivating mutations result in a failure of the border between the anterior and posterior wing compartments. Engrailed is involved in the development of posterior compartments of appendages (Morata and Lawrence, 1975) and segments and the nervous system during development, regulating neural development and embryonic axonal guidance (for overview see: Morgan, 2006; Simon and Alavian, 2009).

Vertebrate Engrailed orthologs

Orthologs of Engrailed have been discovered in many different species. ... ... ... ...
 
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Entry last modified: April 2023