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EVEC

[embryonic vascular EGF-like repeat-containing protein] EVEC is expressed predominantly in the vascular smooth muscle cells of developing arteries in E11.5 through E16.5 mouse embryos. EVEC mRNA expression is downregulated dramatically in adult arteries, except in the uterus, where cyclic angiogenesis continues EVEC expression is reactivated in 2 independent rodent models of vascular injury (Kowal et al, 1999). The protein is identical with Fibulin-5 and DANCE, which are involved in cellular adhesion and act as a growth factor.

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