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ESAM

(approved gene symbol) [endothelial cell-selective adhesion molecule; endothelial cell adhesion molecule] Referred to also as ESAM-1 [endothelial cell-selective adhesion molecule-1]. This cell adhesion molecule (Hirata et al, 2001) is a member of the immunoglobulin superfamily is expressed in cultured human and murine vascular endothelial cells. High level expression is found in lung and heart and low level expression in kidney and skin. ESAM is expressed primarily in the developing vasculature of the embryo in an endothelial cell-restricted pattern. The protein co-localizes with cadherins and catenins in cell-cell junctions and mediates cell-cell adhesion through homophilic ... ... ... ... ... Subscribe to continue reading! ... ...

 

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