ECEF

[Eosinophil cytotoxicity-enhancing factor] also abbr. M-ECEF (Monocyte-derived Eosinophil cytotoxicity-enhancing factor).

This factor is produced by human monocytes stimulated with bacterial lipopolysaccharides. It is secreted also by U937 cells. Multiple forms of this factor (10, 13, 14 kDa) have been described (Balcewicz-Sablinska MK et al, 1991). Membrane-associated ECEF (mECEF), apparently an integral membrane component, is found in U937 cells, in 70 % of monocytes and, at lower levels, on blood T-lymphocytes (Elsas et al, 1990, 1990; Silberstein et al, 1987).

M-ECEF ... ... ... ...
 
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