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Desmopressin

Desmopressin (1-Desamino-8-D-Arginine-vasopressin; abbr. DDAVP) is a synthetic analog of arginine-vasopressin. Desmopressin corresponds to the peptide CYFQNCPRG [Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly].

Among other things, this compound increases the expression of factor VIII and von Willebrand factor in healthy individuals, but, unlike natural vasopressin, it has little or no effect on vasoconstriction, does not increase blood pressure, and has no effect on the contraction of the uterus or gastrointestinal tract (Cash et al, 1974; Mannucci et al, 1975)

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