DC-related cells |
DC-SIGN-1 |
FGF8c |
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[dendritic cell-specific ICAM3-grabbing nonintegrin] also: DC-SIGN-1 [dendritic cell-specific ICAM3-grabbing nonintegrin-1]. This is the same as CD209a [CD209 antigen-like protein A] (see also: CD209). The murine homolog of DC-SIGN has been identified as SIGNR1 [SIGN related gene 1].
This type 2 transmembrane protein protein of 404 amino acids has been identified by Geijtenbeek et al (2000). It is expressed by dendritic cells and binds ICAM-3 expressed on T-cells with high affinity, thus mediating transient adhesion between these two cell types
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