DC-SIGN

[dendritic cell-specific ICAM3-grabbing nonintegrin] also: DC-SIGN-1 [dendritic cell-specific ICAM3-grabbing nonintegrin-1]. This is the same as CD209a [CD209 antigen-like protein A] (see also: CD209). The murine homolog of DC-SIGN has been identified as SIGNR1 [SIGN-Related gene 1].

This type 2 transmembrane protein of 404 amino acids has been identified by Geijtenbeek et al (2000). It is expressed by dendritic cells and binds ICAM3 expressed on T-cells with high affinity, thus mediating transient adhesion between these two cell types ... ... ... ...
 
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