CH domain |
CHEASAAQC |
Hippi |
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Human Che-1 is a protein identified by virtue of its ability to interact with the core subunit of RNA polymerase 2 (hRPB11) (Fanciulli et al, 2000). Che-1 also interacts with the retinoblastoma susceptibility gene (Rb) and represses the growth suppression function of Rb. The protein is identical with AATF [apoptosis antagonizing transcription factor].
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