CFTR

[cystic fibrosis transmembrane conductance regulator] In databanks the protein is being referred to also as ABCC7 [ATP-binding cassette sub-family C member 7] and ABC35.

The term TNR-CFTR refers to a naturally occurring truncated splice variant of CFTR that appears to be expressed specifically in the kidney. This variant contains only the first of two transmembrane domains (TMD), the first of two nucleotide binding domains (NBD), and a regulatory domain (Morales et al, 1996).

CFTR is a multifunctional protein ... ... ... ...
 
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Entry last modified: April 2012