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CD6

[CD6(+), CD6(-)]

Other designations:

OX52

T12

TP120

This antigen is expressed on thymocytes, T-cells, and B-cell chronic lymphocytic leukaemia.

CD6 is a T-cell surface glycoprotein that plays an important role in interactions of thymocytes with thymic epithelial cells and in mature T-cell interactions with selected nonprofessional tissue antigen-presenting cells. The counterreceptor of CD6 is CD166. A second ligand for CD6 has been identified by Saifullah et al (2004). This 130 kDa protein (3A11 protein) is expressed on cells derived from human ... ... ... ... ... Subscribe to continue reading! ... ...

 

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